cardiac myocytes

Browse the Cardiac Epigenome

Posted on2017-12-052018-01-11

The Cardiac Epigenome Browser is a resource for cell-type specific cardiac chromatin interaction and epigenome data. The project is located at the Institute of experimental and clinical Pharmacology and Toxicology, University of Freiburg, and online accessible. The heart is composed more…

Reviewed: Pharmacology of the Mineralocorticoid Receptor

Posted on2015-02-272018-01-04

Aldosterone regulates water and electrolyte homeostasis by activation of the mineralocorticoid receptor (MR), a ligand-activated transcription factor, in the kidney. Clinical trials have shown a striking benefit of MR antagonists in chronic heart failure and post-myocardial infarction treatment. Experimental studies more…