Aldosterone and MR in atrial fibrillation

In our recent article, we review what is currently known about the role of aldosterone and the mineralocorticoid receptor in atrial fibrillation, summarize the mechanistic basis as supported by experimental studies, and discuss the potential of mineralocorticoid receptor antagonists in the prevention and treatment of atrial fibrillation.

Mamazhakypov et al. Hypertension. 2026;83:e26187. DOI: 10.1161/HYPERTENSIONAHA.125.26187