2024 Joint Meeting of ESAC & ADMIRE Network
Registration and abstract submission for the 2024 Joint Meeting of ESAC and the ADMIRE network is now open: meeting.admire-network.org
Tag: mineralocorticoid receptor
Molecular pharmacology of mineralocorticoid receptor antagonists
Mineralocorticoid receptor (MR) antagonists have shown remarkable benefits in the treatment of cardiovascular disease. However, their underutilization in clinical practice may be attributed to concerns regarding the risk of hyperkalemia. An ideal selective MR modulator would inhibit the detrimental effects more…
Therapeutic targeting of mineralocorticoid receptors in pulmonary hypertension
Pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling and associated with adverse outcomes. In patients with PH, plasma aldosterone levels are elevated, suggesting that aldosterone and its receptor, the mineralocorticoid receptor (MR), play an important role in the pathophysiology more…