Increased load leads to cardiac hypertrophy and endothelial cells play a vital role in maintaining oxygen supply to the heart through angiogenesis. However, insufficient angiogenesis contributes to the progression of heart failure. In our latest study, led by Elias Erny, more…
There is emerging evidence that mineralocorticoid receptor antagonists reduce the burden of atrial fibrillation in patients with or without heart failure. In this study, we show that aldosterone infusion drives atrial remodeling in mice and increases the risk for arrhythmia. more…
The heterocellular nature of the heart has been receiving increasing attention in recent years. In addition to cardiomyocytes as the prototypical cell type of the heart, non-myocytes such as endothelial cells, fibroblasts, or immune cells are coming more into focus. more…
