Publications

Please see Data resources for an overview of available transcriptome and epigenome data.

  1. Hamad, MA, Schanze, N, Krauel, K, Lother, A, Perez-Feliz, S, Iaconianni, P, Zurek, M, Almushkab, L, Madl, J, Hollenhorst, MA, Kohl, P, Nührenberg, TG, Duerschmied, D (2026) A transgenic mouse model for reticulated platelet detection reveals expansion after myocardial ischemia/reperfusion. Blood Vessel Thromb Hemost 3 (1):100125. PMID:41573099
  2. Erny, E, Koentges, C, Mukherjee, D, Wirth, L, Kamaras, C, Zell, F, Hossfeld, M, Groß, O, Lother, A (2025) Downregulation of TCF19 and ATAD2 causes endothelial cell cycle arrest at the transition from cardiac hypertrophy to heart failure. Basic Res Cardiol 120 (6):1209-1224. PMID:40962957
  3. Fuchs, J, Karl, V, Hettich, I, Alvarado, J, Eckert, D, Jaki, L, Kohl, AK, Kremser, A, Maks, A, Terschluse, C, Agarwal, P, Emmerich, F, Fähndrich, S, Flügler, A, Hornuss, D, Kalbhenn, J, Kneidinger, N, Lau, I, Lother, A, Moneke, I, Schibilsky, D, Schygulla, E, Venhoff, N, Zissel, G, Czerny, M, Huzly, D, Kochs, G, Neumann-Haefelin, C, Passlick, B, Stolz, D, Thimme, R, Panning, M, Hofmann, M, Frye, BC (2025) SARS-CoV-2 infection dynamics in a MHCI-mismatched lung transplant recipient. Nat Commun 16 (1):8292. PMID:40957936
  4. Sekandarzad, A, Flügler, A, Rheinboldt, A, Rother, D, Först, G, Rieg, S, Supady, A, Lother, A, Staudacher, DL, Wengenmayer, T, Kern, WV, Biever, PM (2025) Reduced antimicrobial consumption through enhanced pneumonia management in critically ill patients: outcomes of an antibiotic stewardship program in the intensive care unit. Front Med (Lausanne) 12 :1549355. PMID:40475964
  5. Meral, D, Mamazhakypov, A, Juncker, K, Calderón-Fernández, M, Peyronnet, R, Zgierski-Johnston, C, Preissl, S, Lother, A (2025) Cell Type-Resolved Transcriptome of Aldosterone-Induced Atrial Myopathy and Arrhythmia. Hypertension 82 (6):e105-e107. PMID:40367219
  6. Rettkowski, J, Romero-Mulero, MC, Singh, I, Wadle, C, Wrobel, J, Chiang, D, Hoppe, N, Mess, J, Schönberger, K, Lalioti, ME, Jäcklein, K, SilvaRego, B, Bühler, T, Karabacz, N, Egg, M, Demollin, H, Obier, N, Zhang, YW, Jülicher, C, Hetkamp, A, Czerny, M, Jones, MJ, Seung, H, Jain, R, von Zur Mühlen, C, Maier, A, Lother, A, Hilgendorf, I, van Galen, P, Kreso, A, Westermann, D, Rodriguez-Fraticelli, AE, Heidt, T, Cabezas-Wallscheid, N (2025) Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study. Nat Cell Biol 27 (4):591-604. PMID:40175666
  7. Lother, A, Staudacher, DL (2025) Inotropes and mortality in patients with cardiogenic shock: more questions than answers. Eur Heart J Cardiovasc Pharmacother 11 (3):290-291. PMID:39919760
  8. Wirth, L, Erny, E, Krane, M, Lahm, H, Hein, L, Gilsbach, R, Lother, A (2024) Gene expression networks in endothelial cells from failing human hearts. Am J Physiol Heart Circ Physiol 327 (3):H573-H581. PMID:39028282
  9. Bode, C, Preissl, S, Hein, L, Lother, A (2024) Catecholamine treatment induces reversible heart injury and cardiomyocyte gene expression. Intensive Care Med Exp 12 (1):48. PMID:38733526
  10. Simon-Chica, A, Klesen, A, Emig, R, Chan, A, Greiner, J, Grün, D, Lother, A, Hilgendorf, I, Rog-Zielinska, EA, Ravens, U, Kohl, P, Schneider-Warme, F, Peyronnet, R (2024) Piezo1 stretch-activated channel activity differs between murine bone marrow-derived and cardiac tissue-resident macrophages. J Physiol 602 (18):4437-4456. PMID:38642051
  11. Deng, L, Pollmeier, L, Bednarz, R, Cao, C, Laurette, P, Wirth, L, Mamazhakypov, A, Bode, C, Hein, L, Gilsbach, R, Lother, A (2024) Atlas of cardiac endothelial cell enhancer elements linking the mineralocorticoid receptor to pathological gene expression. Sci Adv 10 (10):eadj5101. PMID:38446896
  12. Koca, D, Lother, A (2023) Molecular pharmacology of mineralocorticoid receptor antagonists: The role of co-regulators. Steroids 199 :109291. PMID:37558173
  13. Lother, A, Kohl, P (2023) The heterocellular heart: identities, interactions, and implications for cardiology. Basic Res Cardiol 118 (1):30. PMID:37495826
  14. Bojti, I, Przewosnik, AS, Luxenburger, H, Hofmann, M, Neumann-Haefelin, C, Esser, JS, Siegel, PM, Maier, A, Kovacs, SB, Kardos, L, Csanádi, Z, Rieder, M, Duerschmied, D, Lother, A, Bode, C, Szabó, GT, Czuriga, D (2023) Decreased level of serum NT-proCNP associates with disease severity in COVID-19. Respir Res 24 (1):174. PMID:37386635
  15. Mamazhakypov, A, Lother, A (2023) Therapeutic targeting of mineralocorticoid receptors in pulmonary hypertension: Insights from basic research. Front Cardiovasc Med 10 :1118516. PMID:36793473
  16. Rieder, M, Baldus, N, Stallmann, D, Jeserich, M, Goller, I, Wirth, L, Pollmeier, L, Hofmann, M, Bode, C, Busch, HJ, Schmid, B, Gauchel, N, Scharf, RE, Duerschmied, D, Lother, A, Krauel, K (2023) Early SARS-CoV-2 infection: Platelet-neutrophil complexes and platelet function. Res Pract Thromb Haemost 7 (1):100025. PMID:36575689
  17. Ankerhold, J, Giese, S, Kolb, P, Maul-Pavicic, A, Voll, RE, Göppert, N, Ciminski, K, Kreutz, C, Lother, A, Salzer, U, Bildl, W, Welsink, T, Morgenthaler, NG, Grawitz, AB, Emmerich, F, Steinmann, D, Huzly, D, Schwemmle, M, Hengel, H, Falcone, V (2022) Circulating multimeric immune complexes contribute to immunopathology in COVID-19. Nat Commun 13 (1):5654. PMID:36163132
  18. Ngo, V, Fleischmann, BK, Jung, M, Hein, L, Lother, A (2022) Histone Deacetylase 6 Inhibitor JS28 Prevents Pathological Gene Expression in Cardiac Myocytes. J Am Heart Assoc 11 (12):e025857. PMID:35699165
  19. Bauersachs, J, Lother, A (2022) Mineralocorticoid receptor activation and antagonism in cardiovascular disease: cellular and molecular mechanisms. Kidney Int Suppl (2011) 12 (1):19-26. PMID:35529088
  20. Akbil, B, Meyer, T, Stubbemann, P, Thibeault, C, Staudacher, O, Niemeyer, D, Jansen, J, Mühlemann, B, Doehn, J, Tabeling, C, Nusshag, C, Hirzel, C, Sanchez, DS, Nieters, A, Lother, A, Duerschmied, D, Schallner, N, Lieberum, JN, August, D, Rieg, S, Falcone, V, Hengel, H, Kölsch, U, Unterwalder, N, Hübner, RH, Jones, TC, Suttorp, N, Drosten, C, Warnatz, K, Spinetti, T, Schefold, JC, Dörner, T, Sander, LE, Corman, VM, Merle, U, Pa-COVID study Group, Kurth, F, von Bernuth, H, Meisel, C, Goffinet, C (2022) Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies. J Clin Immunol 42 (6):1111-1129. PMID:35511314
  21. Lother, A, Jaisser, F, Wenzel, UO (2022) Emerging fields for therapeutic targeting of the aldosterone-mineralocorticoid receptor signaling pathway. Br J Pharmacol 179 (13):3099-3102. PMID:35174485
  22. Supady, A, Zahn, T, Kuhl, M, Maier, S, Benk, C, Kaier, K, Böttiger, BW, Bode, C, Lother, A, Staudacher, DL, Wengenmayer, T, Duerschmied, D (2022) Cytokine adsorption in patients with post-cardiac arrest syndrome after extracorporeal cardiopulmonary resuscitation (CYTER) - A single-centre, open-label, randomised, controlled trial. Resuscitation 173 :169-178. PMID:35143902
  23. Gauchel, N, Rieder, M, Krauel, K, Goller, I, Jeserich, M, Salzer, U, Venhoff, AC, Baldus, N, Pollmeier, L, Wirth, L, Kern, W, Rieg, S, Busch, HJ, Hofmann, M, Bode, C, Duerschmied, D, Lother, A, Heger, LA (2022) Complement system component dysregulation is a distinctive feature of COVID-19 disease: a prospective and comparative analysis of patients admitted to the emergency department for suspected COVID-19 disease. J Thromb Thrombolysis 53 (4):788-797. PMID:34904186
  24. Clarisse, D, Deng, L, de Bosscher, K, Lother, A (2022) Approaches towards tissue-selective pharmacology of the mineralocorticoid receptor. Br J Pharmacol 179 (13):3235-3249. PMID:34698367
  25. Lother, A, Bode, C, Hein, L (2021) Letter by Lother et al Regarding Article, "Finerenone and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Type 2 Diabetes". Circulation 144 (11):e201. PMID:34516302
  26. Mamazhakypov, A, Hein, L, Lother, A (2022) Mineralocorticoid receptors in pulmonary hypertension and right heart failure: From molecular biology to therapeutic targeting. Pharmacol Ther 231 :107987. PMID:34480966
  27. Greinacher, A, Selleng, K, Mayerle, J, Palankar, R, Wesche, J, Reiche, S, Aebischer, A, Warkentin, TE, Muenchhoff, M, Hellmuth, JC, Keppler, OT, Duerschmied, D, Lother, A, Rieg, S, Gawaz, MP, Mueller, KAL, Scheer, CS, Napp, M, Hahnenkamp, K, Lucchese, G, Vogelgesang, A, Flöel, A, Lovreglio, P, Stufano, A, Marschalek, R, Thiele, T, Immune-Response in COVID-19 Vaccination Study Group (2021) Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein. Blood 138 (14):1269-1277. PMID:34280256
  28. Bauer, A, Schreinlechner, M, Sappler, N, Dolejsi, T, Tilg, H, Aulinger, BA, Weiss, G, Bellmann-Weiler, R, Adolf, C, Wolf, D, Pirklbauer, M, Graziadei, I, Gänzer, H, von Bary, C, May, AE, Wöll, E, von Scheidt, W, Rassaf, T, Duerschmied, D, Brenner, C, Kääb, S, Metzler, B, Joannidis, M, Kain, HU, Kaiser, N, Schwinger, R, Witzenbichler, B, Alber, H, Straube, F, Hartmann, N, Achenbach, S, von Bergwelt-Baildon, M, von Stülpnagel, L, Schoenherr, S, Forer, L, Embacher-Aichhorn, S, Mansmann, U, Rizas, KD, Massberg, S, ACEI-COVID investigators (2021) Discontinuation versus continuation of renin-angiotensin-system inhibitors in COVID-19 (ACEI-COVID): a prospective, parallel group, randomised, controlled, open-label trial. Lancet Respir Med 9 (8):863-872. PMID:34126053
  29. Kimura, K, Ooms, A, Graf-Riesen, K, Kuppusamy, M, Unger, A, Schuld, J, Daerr, J, Lother, A, Geisen, C, Hein, L, Takahashi, S, Li, G, Röll, W, Bloch, W, van der Ven, PFM, Linke, WA, Wu, SM, Huesgen, PF, Höhfeld, J, Fürst, DO, Fleischmann, BK, Hesse, M (2021) Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy. Nat Commun 12 (1):3575. PMID:34117258
  30. Supady, A, Weber, E, Rieder, M, Lother, A, Niklaus, T, Zahn, T, Frech, F, Müller, S, Kuhl, M, Benk, C, Maier, S, Trummer, G, Flügler, A, Krüger, K, Sekandarzad, A, Stachon, P, Zotzmann, V, Bode, C, Biever, PM, Staudacher, D, Wengenmayer, T, Graf, E, Duerschmied, D (2021) Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation (CYCOV): a single centre, open-label, randomised, controlled trial. Lancet Respir Med 9 (7):755-762. PMID:34000236
  31. Kowalski, J, Deng, L, Suennen, C, Koca, D, Meral, D, Bode, C, Hein, L, Lother, A (2021) Eplerenone Improves Pulmonary Vascular Remodeling and Hypertension by Inhibition of the Mineralocorticoid Receptor in Endothelial Cells. Hypertension 78 (2):456-465. PMID:33966455
  32. Rieder, M, Duerschmied, D, Bode, C, Lother, A (2021) Reply to Panda et al. J Infect Dis 224 (2):367-368. PMID:33955472
  33. Bemtgen, X, Rilinger, J, Jäckel, M, Zotzmann, V, Supady, A, Benk, C, Bode, C, Wengenmayer, T, Lother, A, Staudacher, DL (2021) Admission blood glucose level and outcome in patients requiring venoarterial extracorporeal membrane oxygenation. Clin Res Cardiol 110 (9):1484-1492. PMID:33944987
  34. Supady, A, Zahn, T, Rieder, M, Benk, C, Lother, A, Bode, C, Wengenmayer, T, Staudacher, D, Kellum, JA, Duerschmied, D (2022) Effect of Cytokine Adsorption on Survival and Circulatory Stabilization in Patients Receiving Extracorporeal Cardiopulmonary Resuscitation. ASAIO J 68 (1):64-72. PMID:33883508
  35. Simon-Chica, A, Fernández, MC, Wülfers, EM, Lother, A, Hilgendorf, I, Seemann, G, Ravens, U, Kohl, P, Schneider-Warme, F (2022) Novel insights into the electrophysiology of murine cardiac macrophages: relevance of voltage-gated potassium channels. Cardiovasc Res 118 (3):798-813. PMID:33823533
  36. Biever, P, Staudacher, DL, Sommer, MJ, Triebel, H, Neukamm, MA, Bode, C, Supady, A, Lother, A (2021) Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID-19. Pharmacol Res Perspect 9 (2):e00743. PMID:33710753
  37. Rieder, M, Duerschmied, D, Zahn, T, Lang, C, Benk, C, Lother, A, Biever, P, Bode, C, Wengenmayer, T, Staudacher, D, Supady, A (2021) Cytokine Adsorption in Severe Acute Respiratory Failure Requiring Veno-Venous Extracorporeal Membrane Oxygenation. ASAIO J 67 (3):332-338. PMID:33627609
  38. Hesse, M, Bednarz, R, Carls, E, Becker, C, Bondareva, O, Lother, A, Geisen, C, Dreßen, M, Krane, M, Roell, W, Hein, L, Fleischmann, BK, Gilsbach, R (2021) Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes. J Mol Cell Cardiol 152 :95-104. PMID:33290769
  39. Rieder, M, Wirth, L, Pollmeier, L, Jeserich, M, Goller, I, Baldus, N, Schmid, B, Busch, HJ, Hofmann, M, Thimme, R, Rieg, S, Kern, W, Bode, C, Duerschmied, D, Lother, A (2021) Serum Protein Profiling Reveals a Specific Upregulation of the Immunomodulatory Protein Progranulin in Coronavirus Disease 2019. J Infect Dis 223 (5):775-784. PMID:33249471
  40. Rieder, M, Bode, C, Duerschmied, D, Lother, A (2021) Response to "How Important Is the Assessment of Soluble ACE-2 in COVID-19?". Am J Hypertens 34 (3):298. PMID:33201224
  41. Lother, A, Bondareva, O, Saadatmand, AR, Pollmeier, L, Härdtner, C, Hilgendorf, I, Weichenhan, D, Eckstein, V, Plass, C, Bode, C, Backs, J, Hein, L, Gilsbach, R (2021) Diabetes changes gene expression but not DNA methylation in cardiac cells. J Mol Cell Cardiol 151 :74-87. PMID:33197445
  42. Rieder, M, Wirth, L, Pollmeier, L, Jeserich, M, Goller, I, Baldus, N, Schmid, B, Busch, HJ, Hofmann, M, Kern, W, Bode, C, Duerschmied, D, Lother, A (2021) Serum ACE2, Angiotensin II, and Aldosterone Levels Are Unchanged in Patients With COVID-19. Am J Hypertens 34 (3):278-281. PMID:33043967
  43. Rieder, M, Zahn, T, Benk, C, Lother, A, Bode, C, Staudacher, D, Duerschmied, D, Supady, A (2021) Cytokine adsorption in a patient with severe coronavirus disease 2019 related acute respiratory distress syndrome requiring extracorporeal membrane oxygenation therapy: A case report. Artif Organs 45 (2):191-194. PMID:32929761
  44. Lother, A, Kaier, K, Ahrens, I, Bothe, W, Wolf, D, Zehender, M, Bode, C, von Zur Mühlen, C, Stachon, P (2020) Bleeding Complications Drive In-Hospital Mortality of Patients with Atrial Fibrillation after Transcatheter Aortic Valve Replacement. Thromb Haemost 120 (11):1580-1586. PMID:32828074
  45. Supady, A, Duerschmied, D, Bode, C, Rieder, M, Lother, A (2020) Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19. Crit Care 24 (1):514. PMID:32819415
  46. Lother, A (2020) Mineralocorticoid Receptors: Master Regulators of Extracellular Matrix Remodeling. Circ Res 127 (3):354-356. PMID:32673533
  47. Rieder, M, Goller, I, Jeserich, M, Baldus, N, Pollmeier, L, Wirth, L, Supady, A, Bode, C, Busch, HJ, Schmid, B, Duerschmied, D, Gauchel, N, Lother, A (2020) Rate of venous thromboembolism in a prospective all-comers cohort with COVID-19. J Thromb Thrombolysis 50 (3):558-566. PMID:32617807
  48. Lang, CN, Sommer, MJ, Neukamm, MA, Staudacher, DL, Supady, A, Bode, C, Duerschmied, D, Lother, A (2020) Use of the CytoSorb adsorption device in MDMA intoxication: a first-in-man application and in vitro study. Intensive Care Med Exp 8 (1):21. PMID:32542550
  49. Decker, A, Welzel, M, Laubner, K, Grundmann, S, Kochs, G, Panning, M, Thimme, R, Bode, C, Wagner, D, Lother, A (2020) Prolonged SARS-CoV-2 shedding and mild course of COVID-19 in a patient after recent heart transplantation. Am J Transplant 20 (11):3239-3245. PMID:32519406
  50. Deng, L, Pollmeier, L, Zhou, Q, Bergemann, S, Bode, C, Hein, L, Lother, A (2020) Gene expression in immortalized versus primary isolated cardiac endothelial cells. Sci Rep 10 (1):2241. PMID:32042042
  51. Lother, A, Benk, C, Staudacher, DL, Supady, A, Bode, C, Wengenmayer, T, Duerschmied, D (2019) Cytokine Adsorption in Critically Ill Patients Requiring ECMO Support. Front Cardiovasc Med 6 :71. PMID:31275944
  52. Lother, A, Bode, C, Staudacher, DL (2019) Tracheostomy in Patients on Extracorporeal Membrane Oxygenation: Is it Really Safe?. J Intensive Care Med :885066619851067. PMID:31122107
  53. Lother, A, Deng, L, Huck, M, Fürst, D, Kowalski, J, Esser, JS, Moser, M, Bode, C, Hein, L (2019) Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis. J Endocrinol 240 (1):15-26. PMID:30400069
  54. Rommel, C, Rösner, S, Lother, A, Barg, M, Schwaderer, M, Gilsbach, R, Bömicke, T, Schnick, T, Mayer, S, Doll, S, Hesse, M, Kretz, O, Stiller, B, Neumann, FJ, Mann, M, Krane, M, Fleischmann, BK, Ravens, U, Hein, L (2018) The Transcription Factor ETV1 Induces Atrial Remodeling and Arrhythmia. Circ Res 123 (5):550-563. PMID:29930145
  55. Lother, A, Bergemann, S, Deng, L, Moser, M, Bode, C, Hein, L (2018) Cardiac Endothelial Cell Transcriptome. Arterioscler Thromb Vasc Biol 38 (3):566-574. PMID:29301788
  56. Lother, A, Bergemann, S, Kowalski, J, Huck, M, Gilsbach, R, Bode, C, Hein, L (2018) Inhibition of the cardiac myocyte mineralocorticoid receptor ameliorates doxorubicin-induced cardiotoxicity. Cardiovasc Res 114 (2):282-290. PMID:28430882
  57. Esser, JS, Charlet, A, Schmidt, M, Heck, S, Allen, A, Lother, A, Epting, D, Patterson, C, Bode, C, Moser, M (2017) The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovasc Res 113 (2):222-223. PMID:28082451
  58. Beetz, N, Rommel, C, Schnick, T, Neumann, E, Lother, A, Monroy-Ordonez, EB, Zeeb, M, Preissl, S, Gilsbach, R, Melchior-Becker, A, Rylski, B, Stoll, M, Schaefer, L, Beyersdorf, F, Stiller, B, Hein, L (2016) Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload. J Mol Cell Cardiol 101 :145-155. PMID:27789290
  59. Lother, A, Hein, L (2016) Pharmacology of heart failure: From basic science to novel therapies. Pharmacol Ther 166 :136-49. PMID:27456554
  60. Lother, A, Wengenmayer, T, Benk, C, Bode, C, Staudacher, DL (2016) Fatal air embolism as complication of percutaneous dilatational tracheostomy on venovenous extracorporeal membrane oxygenation, two case reports. J Cardiothorac Surg 11 (1):102. PMID:27401983
  61. Lother, A, Hein, L (2016) Vascular Mineralocorticoid Receptors: Linking Risk Factors, Hypertension, and Heart Disease. Hypertension 68 (1):6-10. PMID:27217405
  62. Lother, A, Beyersdorf, F, Osterhues, HH, Bode, C, Wengenmayer, T (2016) Recurrent pulseless electrical activity in a patient with coronary vasospasm and supravalvular aortic stenosis: a case report. BMC Cardiovasc Disord 16 :100. PMID:27216437
  63. Lother, A, Fürst, D, Bergemann, S, Gilsbach, R, Grahammer, F, Huber, TB, Hilgendorf, I, Bode, C, Moser, M, Hein, L (2016) Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure. Hypertension 67 (1):130-8. PMID:26553231
  64. Koentges, C, Pfeil, K, Meyer-Steenbuck, M, Lother, A, Hoffmann, MM, Odening, KE, Hein, L, Bode, C, Bugger, H (2016) Preserved recovery of cardiac function following ischemia-reperfusion in mice lacking SIRT3. Can J Physiol Pharmacol 94 (1):72-80. PMID:26524632
  65. Mayer, SC, Gilsbach, R, Preissl, S, Monroy Ordonez, EB, Schnick, T, Beetz, N, Lother, A, Rommel, C, Ihle, H, Bugger, H, Rühle, F, Schrepper, A, Schwarzer, M, Heilmann, C, Bönisch, U, Gupta, SK, Wilpert, J, Kretz, O, von Elverfeldt, D, Orth, J, Aktories, K, Beyersdorf, F, Bode, C, Stiller, B, Krüger, M, Thum, T, Doenst, T, Stoll, M, Hein, L (2015) Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure. Circ Res 117 (7):622-33. PMID:26195221
  66. Lother, A, Moser, M, Bode, C, Feldman, RD, Hein, L (2015) Mineralocorticoids in the heart and vasculature: new insights for old hormones. Annu Rev Pharmacol Toxicol 55 :289-312. PMID:25251996
  67. Volkmann, I, Kumarswamy, R, Pfaff, N, Fiedler, J, Dangwal, S, Holzmann, A, Batkai, S, Geffers, R, Lother, A, Hein, L, Thum, T (2013) MicroRNA-mediated epigenetic silencing of sirtuin1 contributes to impaired angiogenic responses. Circ Res 113 (8):997-1003. PMID:23960241
  68. Schneider, J, Lother, A, Hein, L, Gilsbach, R (2011) Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis. Basic Res Cardiol 106 (4):591-602. PMID:21547520
  69. Lother, A, Berger, S, Gilsbach, R, Rösner, S, Ecke, A, Barreto, F, Bauersachs, J, Schütz, G, Hein, L (2011) Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. Hypertension 57 (4):746-54. PMID:21321305
  70. Gilsbach, R, Schneider, J, Lother, A, Schickinger, S, Leemhuis, J, Hein, L (2010) Sympathetic alpha(2)-adrenoceptors prevent cardiac hypertrophy and fibrosis in mice at baseline but not after chronic pressure overload. Cardiovasc Res 86 (3):432-42. PMID:20083574
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