Call for Papers: Emerging fields for therapeutic targeting of the aldosterone-mineralocorticoid receptor signaling pathway

The British Journal of Pharmacology will be publishing a special ‘Themed Issue’ entitled “Emerging fields for therapeutic targeting of the aldosterone-mineralocorticoid receptor signaling pathway” with Achim Lother, Ulrich Wenzel and Frédéric Jaisser as Guest Editors. Call for papers: https://bpspubs.onlinelibrary.wiley.com/hub/journal/14765381/aldosterone-mineralocorticoid.html

No increased activity of the renin-angiotensin-aldosterone system in patients with COVID-19

The role of the renin-angiotensin-aldosterone system in the corona virus-induced disease COVID-19 is controversially discussed. SARS-CoV-2 enters host cells by binding to angiotensin-converting enzyme 2 and activity of the renin-angiotensin-aldosterone system may affect susceptibility to SARS-CoV-2 infection and outcome of more…

Mineralocorticoid Receptors: Master Regulators of Extracellular Matrix Remodeling

Mineralocorticoid receptors control extracellular matrix composition in the left ventricle and also extracardiac tissues. In the present issue of Circulation Research, the group of Natalia Lopez further extend this view, demonstrating that the aldosterone/MR signaling pathway drives mitral valve remodeling more…