Catecholamines are commonly used as therapeutic drugs in intensive care medicine to maintain sufficient organ perfusion during shock. However, excessive or sustained adrenergic activation drives detrimental cardiac remodeling and may lead to heart failure. Whether catecholamine treatment in absence of more…
It was hypothesized that increased cytokine levels may lead to negative outcomes of patients with severe COVID-19. In a single-centre, open-label, randomized, controlled trial conducted at the Freiburg University Medical Center 34 patients with severe COVID-19 requiring ECMO therapy were more…
Both, antiviral treatment with remdesivir and hemoadsorption using a CytoSorb® adsorption device are applied in the treatment of severe COVID-19. The CytoSorb® adsorber consists of porous polymer beads that adsorb a broad range of molecules, including cytokines but also several more…
