The role of the renin-angiotensin-aldosterone system in the corona virus-induced disease COVID-19 is controversially discussed. SARS-CoV-2 enters host cells by binding to angiotensin-converting enzyme 2 and activity of the renin-angiotensin-aldosterone system may affect susceptibility to SARS-CoV-2 infection and outcome of more…
Mineralocorticoid receptors control extracellular matrix composition in the left ventricle and also extracardiac tissues. In the present issue of Circulation Research, the group of Natalia Lopez further extend this view, demonstrating that the aldosterone/MR signaling pathway drives mitral valve remodeling more…
“Aldosterone-Mineralocorticoid Receptor – Cell Biology to Translational Medicine” edited by Brian Harvey is now online. The open-access book assembles review chapters from 16 European laboratories taking part in the EU COST Action ADMIRE on Aldosterone and the Mineralocorticoid Receptor. It more…
